- Why is Gregor Mendel often referred to as the "Founder of
- What ratios of offspring arise in each of the generations (F1
and F2) in a typical monohybrid cross?
- Understand the following ideas related to Mendel's Law of
Apply Mendel's Law of Segregation to an actual monohybrid cross
trait. What is the phenotype and genotype (i.e. homozygous
dominant, homozygous recessive, heterozygous) of the parents and
in the crosses? What phenotypic and genotypic ratios
result from a basic monohybrid cross?
What is a test cross? Why might a geneticist do a
What is a dihybrid cross? What phenotypic ratios
a Mendelian dihybrid cross? Apply Mendel's Law of Independent
Assortment to an actual dihybrid cross. If two traits
or are inherited independently, what does this mean in terms of the
location of their loci on chromosomes, and how they "assort"
How do Mendel's laws of inheritance reflect the specific
the rules of probability? Be able to apply these laws of
and rules of probability to genetics problems (see problems at the end
of this chapter).
Be able to extend Mendelian genetic principles to understand and
problems related to alternative patterns not reported by Mendel:
- Alternate versions of genes (different alleles) account
in inherited characters.
- For each character, an organism inherits two alleles, one from
- The difference between dominant and recessive
- The segregation of alleles during meiosis.
What is the difference between dominance and recessiveness at
organismal and molecular level?
What else determines phenotype besides genotype?
Be familiar with some human genetic disorders that follow
of inheritance (cystic fibrosis, Tay-Sachs, Sickle Cell Anemia).
Why are lethal or deleterious dominant alleles so rare in populations?
What are some ways of testing a fetus for genetic disorders?
- Incomplete Dominance
- Multiple alleles for a given gene.
- Polygenic Inheritance