Path from Gene to Protein

1.    What is the one gene - one polypeptide hypothesis?  Discuss the early experimental evidence (the work of Beadle and Tatum) that supported this hypothesis.

2.    Review the structure of RNA.  How is it different from that of DNA?

3.    How are genes transcribed into a mRNA transcript?

4.    What modifications must the primary mRNA transcript undergo before it can be translated? 5. Describe the nature of the genetic code. 6.    Describe the process of translation. 7.    Describe the general characteristics of mutations.